Clostridium difficile – diagnostics and treatment – clinical cases

Treatment of Clostridium difficile infection.

Recent outbreaks of Clostridium difficile infection (CDI) in North America have been due to a more virulent, possibly more resistant strain that causes more-severe disease, making prompt recognition of cases and optimal management of infection essential for a successful therapeutic outcome. Treatment algorithms are presented to help guide the management of patients with CDI. Metronidazole has b...

1660Risk of Recurrent Clostridium difficile Infection: Impact of Diagnostics and Treatment

Diagnostics and Treatment Sujan C. Reddy, MD; Olivia M. Almendares, MSPH; Wendy Baughman, MSPH; Fernanda C. Lessa, MD; Monica M. Farley, MD; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA; Georgia Emerging Infections Program, Decatur, GA; Atlanta Research and Education Foundation, Decatur, GA; Atlanta VAMedical Center, Decatur, GA; Division of Healthcare Quali...

Clostridium difficile associated diarrhoea: diagnosis and treatment.

Clostridium difficile outbreaks: prevention and treatment strategies

The incidence and severity of Clostridium difficile infection (CDI) have increased dramatically over the past decade. Its treatment, however, has largely remained the same with the exception of oral vancomycin use as a first-line agent in severe disease. From 1999 to 2004, 20,642 deaths were attributed to CDI in the United States, almost 7 times the rate of all other intestinal infections combi...

Toxin profiles and antimicrobial resistance patterns among toxigenic clinical isolates of Clostridioides (Clostridium) difficile

Objective(s): Clostridioides (Clostridium) difficile infection as a healthcare-associated infection can cause life-threatening infectious diarrhea in hospitalized patients. The aim of this study was to investigate the toxin profiles and antimicrobial resistance patterns of C. difficile isolates obtained from hospitalized patients in Shiraz, Iran.Mater...